Cache Cleaner

After installing Cache Cleaner v8.2.1 (Free)
When an article is opened for editing (with JCE) and I press 'Save':

HTTP 500 Whoops, it looks like something went wrong.

Exceptions 2

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INFO:
Joomla 4.2.3
PHP 8.1.x
Template - Child of Cassiopeia
'System Cache' is ON - Conservative - File
Plugin 'System - Page Cache' if OFF

Some additional code in .htaccess may be involved in this error, but I'm not sure.

Yes, same error after performing suggested actions.
Manually cache clearing doesn't remove the following items (or they are immediately recreated, not sure) -
_media_version
_system
com_plugins

All inside 'administrator/cache' folder was deleted except index.html

As I said this error appears after pressing 'Save' when editing an article, but I didn't check any other scenarios yet.
After refreshing the browser administrative section is shown normally, so this error disappears just by browser refresh.
The article is saved normally, the error is mostly annoying.

EDIT: When switching off plugin 'System - Regular Labs - Cache Cleaner', same error is shown, but for the last time.

Moved to the end of system plugins to no avail.
On the other hand, Cache Cleaner is working without such an error on localhost under XAMPP for Windows, same Joomla 4.2.3, PHP 8.1.6 and the same number of running plugins.
So the problem could be in server configuration probably.

Just open any article and try to 'Save and Close', in case no error on the first attempt, try to add space character anywhere in the article (just to be not visible to users) and 'Save and Close'.

Thank you! So far no errors. I will revoke your access within a day. Ask me if you want to check anything else.